Description

4-(5-Trifluoromethyl-Tetrazol-1-Yl)-Phenol is a high-value, multi-functional heterocyclic building block characterized by its phenol and tetrazole motifs. This compound is essential for advanced research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and specific physicochemical properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas requiring bioisosteric replacement or modulation of pharmacokinetic properties.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the stability and activity of the trifluoromethyl-tetrazole group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of novel polymers and functional materials where the phenol group allows for further polymerization or derivatization.
• Chemical Biology Probes: Useful in designing molecular probes and tags for studying biological systems due to its distinct chemical handle.

Basic Information

Product Name	4-(5-Trifluoromethyl-Tetrazol-1-Yl)-Phenol
CAS No.	168267-75-2
Molecular Formula	C8H5F3N4O
Molecular Weight	230.15 g/mol
Synonyms	4-(5-(Trifluoromethyl)-1H-tetrazol-1-yl)phenol; 1-(4-Hydroxyphenyl)-5-(trifluoromethyl)-1H-tetrazole; Phenol, 4-[5-(trifluoromethyl)-1H-tetrazol-1-yl]-; 4-(5-Trifluoromethyl-1H-tetrazol-1-yl)phenol; 4-(5-Trifluoromethyltetrazol-1-yl)phenol; 1-(4-Hydroxyphenyl)-5-trifluoromethyltetrazole; 4-(5-Trifluoromethyltetrazolyl)phenol
EINECS	Contact for details

Quality Control

Our 4-(5-Trifluoromethyl-Tetrazol-1-Yl)-Phenol is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.