Description

tert-Butyl 4-Bromonaphthalen-1-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its naphthalene core and bromo-substituted carbamate functional group. This compound is a critical building block in modern organic synthesis, enabling the construction of complex molecules with high precision. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Organic Synthesis Building Block: Used in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the 4-bromonaphthalene moiety into larger molecular architectures.
• Agrochemical Research: Serves as a starting material for developing new crop protection agents and herbicides with specific activity profiles.
• Material Science: Employed in the research and development of organic semiconductors, liquid crystals, and advanced polymers due to its rigid, aromatic structure.
• Chemical Biology & Proteomics: Can be utilized as a scaffold or labeling agent in the design of molecular probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	tert-Butyl 4-Bromonaphthalen-1-Ylcarbamate
CAS No.	168169-11-7
Molecular Formula	C15H16BrNO2
Molecular Weight	322.20 g/mol
Synonyms	1-Naphthalenol, 4-bromo-, 1-(1,1-dimethylethyl) carbamate; 4-Bromo-1-naphthyl tert-butylcarbamate; tert-Butyl N-(4-bromonaphthalen-1-yl)carbamate; 1-(tert-Butoxycarbonylamino)-4-bromonaphthalene; 4-Bromo-1-((tert-butoxycarbonyl)amino)naphthalene; Boc-4-Bromo-1-naphthylamine; N-Boc-4-bromo-1-naphthylamine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-Bromonaphthalen-1-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.