Description

Dl-2-Amino-4-(4-Methoxyphenyl)-4-Oxobutanoic Acid Hcl is a high-purity, non-natural amino acid derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral building block and intermediate for the development of novel pharmaceutical agents and bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of complex peptide mimetics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Research: Used as a constrained amino acid analog in structure-activity relationship (SAR) studies to modulate peptide conformation, potency, and metabolic stability.
• Peptidomimetic Synthesis: Essential for constructing non-natural peptide backbones that mimic natural peptides but with enhanced bioavailability and resistance to enzymatic degradation.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or probes for studying enzyme mechanisms and protein-protein interactions.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for candidate drugs.
• Academic Research: Used in university and institutional labs for methodological development in asymmetric synthesis and heterocyclic chemistry.

Basic Information

Product Name	Dl-2-Amino-4-(4-Methoxyphenyl)-4-Oxobutanoic Acid Hcl
CAS No.	168154-99-2
Molecular Formula	C11H14ClNO4
Molecular Weight	259.69 g/mol
Synonyms	DL-2-Amino-4-(4-methoxyphenyl)-4-oxobutanoic acid hydrochloride; 4-Methoxy-DL-phenylalanine derivative HCl; 2-Amino-4-(4-methoxyphenyl)-4-oxobutanoic acid hydrochloride (racemic); (±)-2-Amino-4-(4-methoxyphenyl)-4-oxobutanoic acid HCl; 4-(4-Methoxyphenyl)-2-aminosuccinic acid 4-methyl ester hydrochloride; (RS)-2-Amino-4-(4-methoxyphenyl)-4-oxobutanoic acid hydrochloride; 4-Methoxybenzoylalanine hydrochloride; NSC 760439 (Hydrochloride)
EINECS	Contact for details

Quality Control

Our Dl-2-Amino-4-(4-Methoxyphenyl)-4-Oxobutanoic Acid Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Racemic mixture (DL)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.