Description

1,3,2-Dioxathiolane,4-(1-Methylethyl)-,2,2-Dioxide,(4S)-(9Ci) is a high-purity, chiral sulfone derivative of significant interest in advanced organic synthesis. This compound serves as a valuable chiral building block and intermediate for the development of novel pharmaceuticals and fine chemicals. It is primarily utilized by research institutions and industrial R&D departments focused on asymmetric synthesis, medicinal chemistry, and the production of enantiomerically pure substances.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Employed as a chiral auxiliary or a precursor to chiral ligands and catalysts in stereoselective chemical transformations.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to introduce specific stereochemistry.
• Fine Chemical Production: Serves as a building block for the synthesis of complex, high-value specialty chemicals requiring defined stereochemistry.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry and process chemistry within university and corporate laboratories.

Basic Information

Product Name	1,3,2-Dioxathiolane,4-(1-Methylethyl)-,2,2-Dioxide,(4S)-(9Ci)
CAS No.	168141-49-9
Molecular Formula	C5H10O4S
Molecular Weight	166.20 g/mol
Synonyms	(4S)-4-Isopropyl-1,3,2-dioxathiolane 2,2-dioxide; (S)-4-Isopropyl-1,3,2-dioxathiolane-2,2-dioxide; (S)-4-(1-Methylethyl)-1,3,2-dioxathiolane 2,2-dioxide; (S)-Isopropyl sulfite cyclic; Chiral isopropyl sulfite; (S)-Cyclic isopropyl sulfite; (4S)-4-(Propan-2-yl)-1,3,2-dioxathiolane 2,2-dioxide
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxathiolane,4-(1-Methylethyl)-,2,2-Dioxide,(4S)-(9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and chemical assay, to support your critical R&D and scale-up activities. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (ee, HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.