Description

4-Hydroxy-2-oxo-N-(thiazol-2-yl)-1,2-dihydroquinoline-3-carboxamide is a specialized heterocyclic organic compound featuring a fused quinoline core linked to a thiazole ring via a carboxamide bridge. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Acts as a key intermediate in the research and production of new-generation pesticides and herbicides.
• Chemical Biology Probe: Utilized in biochemical assays to study enzyme inhibition or protein-ligand interactions due to its specific heterocyclic structure.
• Organic Synthesis Reference Standard: Employed as a high-purity standard for analytical method development and validation in QC laboratories.

Basic Information

Product Name	4-Hydroxy-2-oxo-N-(thiazol-2-yl)-1,2-dihydroquinoline-3-carboxamide
CAS No.	167565-14-2
Molecular Formula	C₁₃H₉N₃O₃S
Molecular Weight	287.29 g/mol
Synonyms	4-Hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acid (2-thiazolyl)amide; 4-Hydroxy-1,2-dihydro-2-oxo-N-2-thiazolylquinoline-3-carboxamide; 1,2-Dihydro-4-hydroxy-2-oxo-N-2-thiazolyl-3-quinolinecarboxamide; 3-Quinolinecarboxamide, 1,2-dihydro-4-hydroxy-2-oxo-N-2-thiazolyl-; N-(Thiazol-2-yl)-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide; 4-Hydroxy-2-oxo-N-(1,3-thiazol-2-yl)-1,2-dihydroquinoline-3-carboxamide
EINECS	Contact for details

Quality Control

Every batch of our 4-Hydroxy-2-oxo-N-(thiazol-2-yl)-1,2-dihydroquinoline-3-carboxamide is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard pharmaceutical intermediate grade meets high-purity requirements suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identification by spectroscopic methods, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.