Description

Ethyl 4,5,6,7-Tetrahydro-1H-Benzo[D]Imidazole-6-Carboxylate Hydrochloride is a high-purity, pharmaceutically relevant organic salt, serving as a critical building block in modern synthetic chemistry. Its value lies in its role as a versatile intermediate for constructing complex nitrogen-containing heterocycles, which are core structures in numerous active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking reliable, high-quality intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and metabolic conditions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the imidazole moiety's bioactivity.
• Fine Chemical Synthesis: Serves as a specialized building block for creating complex molecules in custom synthesis and contract manufacturing projects.
• Academic & R&D Laboratories: Employed in methodological studies and the discovery of new chemical reactions and catalytic processes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	Ethyl 4,5,6,7-Tetrahydro-1H-Benzo[D]Imidazole-6-Carboxylate Hydrochloride
CAS No.	167545-99-5
Molecular Formula	C10H15N2O2·HCl
Molecular Weight	228.70 g/mol (Free base: 195.24 g/mol)
Synonyms	Ethyl 4,5,6,7-tetrahydro-1H-benzimidazole-6-carboxylate hydrochloride; 6-Carbethoxy-4,5,6,7-tetrahydrobenzimidazole hydrochloride; 1H-Benzimidazole-6-carboxylic acid, 4,5,6,7-tetrahydro-, ethyl ester, hydrochloride; Ethyl 4,5,6,7-tetrahydro-1H-benzimidazole-6-carboxylate HCl; 6-Ethoxycarbonyl-4,5,6,7-tetrahydrobenzimidazole hydrochloride
EINECS	Contact for details

Quality Control

Every batch of Ethyl 4,5,6,7-Tetrahydro-1H-Benzo[D]Imidazole-6-Carboxylate Hydrochloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for pharmaceutical intermediates. Comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, is performed to guarantee identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent exposure to atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.