Description

1'-(Benzyloxycarbonyl)Spiro(Indoline-3,4'-Piperidine) is a sophisticated spirocyclic organic building block of significant interest in advanced pharmaceutical research and development. Its core value lies in its unique molecular architecture, which serves as a privileged scaffold for constructing novel bioactive compounds targeting central nervous system and other therapeutic areas. This high-purity intermediate is primarily needed by medicinal chemists and process development scientists within pharmaceutical, biotechnology, and fine chemical synthesis companies engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in hit-to-lead optimization.
• Protease Inhibitor Synthesis: Used in the construction of complex molecules designed to inhibit specific enzymatic targets.
• GPCR Ligand Development: Employed as a core structure for designing ligands targeting G-protein-coupled receptors.
• Chemical Biology Probes: Utilized to create tool compounds for investigating biological pathways and target validation.
• Process Chemistry & Scale-Up: Provides a defined starting point for developing robust, scalable synthetic routes to active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1'-(Benzyloxycarbonyl)Spiro(Indoline-3,4'-Piperidine)
CAS No.	167484-18-6
Molecular Formula	C21H22N2O2
Molecular Weight	334.42 g/mol
Synonyms	Spiro[indoline-3,4'-piperidine]-1'-carboxylic acid benzyl ester; 1-N-CBZ-spiro[indoline-3,4'-piperidine]; 1'-(Benzyloxycarbonyl)spiro[indoline-3,4'-piperidine]; 1'-CBZ-Spiro(indoline-3,4'-piperidine); Benzyl 1'-azaspiro[indoline-3,4'-piperidine]-1'-carboxylate; 1'-Benzyloxycarbonylspiro(indoline-3,4'-piperidine); 1'-N-Cbz-1'-azaspiro[indoline-3,4'-piperidine]; (1'Benzyloxycarbonyl)spiro(indoline-3,4'-piperidine)
EINECS	Contact for details

Quality Control

Our 1'-(Benzyloxycarbonyl)Spiro(Indoline-3,4'-Piperidine) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.