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n-[4-Chloro-2-Nitro-5-(Trifluoromethyl)Phenyl]-2,2,2-Trifluoroacetamide CAS NO 167415-21-6


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CAS No.:167415-21-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-[4-Chloro-2-Nitro-5-(Trifluoromethyl)Phenyl]-2,2,2-Trifluoroacetamide is a specialized fluorinated aromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both nitro and multiple trifluoromethyl groups, makes it a valuable intermediate for creating complex molecules with tailored properties. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
  • Agrochemical Synthesis: Serves as a core building block for developing next-generation herbicides and pesticides with enhanced efficacy and environmental profiles.
  • Material Science Research: Used in the creation of specialty polymers and advanced materials where fluorination imparts desired properties like chemical resistance or thermal stability.
  • Organic Synthesis & Catalysis: A versatile reagent for constructing complex aromatic systems in academic and industrial research settings.
  • Fluorine Chemistry: An important compound for studying structure-activity relationships (SAR) in fluorinated molecules.

Basic Information

Product Name n-[4-Chloro-2-Nitro-5-(Trifluoromethyl)Phenyl]-2,2,2-Trifluoroacetamide
CAS No. 167415-21-6
Molecular Formula C9H3ClF6N2O3
Molecular Weight 336.57 g/mol
Synonyms 2,2,2-Trifluoro-N-[4-chloro-2-nitro-5-(trifluoromethyl)phenyl]acetamide; N-(4-Chloro-2-nitro-5-(trifluoromethyl)phenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoroacetamide, N-[4-chloro-2-nitro-5-(trifluoromethyl)phenyl]-; 4-Chloro-2-nitro-5-(trifluoromethyl)phenyl trifluoroacetamide; CAS 167415-21-6; TFAPA derivative; Fluorinated nitroaniline acetamide
EINECS Contact for details

Quality Control

Our production of n-[4-Chloro-2-Nitro-5-(Trifluoromethyl)Phenyl]-2,2,2-Trifluoroacetamide adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with REACH and other global regulatory frameworks, and our quality systems are designed to meet the exacting standards of pharmaceutical and agrochemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider inert atmosphere conditions to maintain product integrity.

Specification

Item Specification
Appearance Off-white to pale yellow crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point Contact for details
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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