Description

(E)-3-(2-(5,6,7,8-Tetrahydro-3,5,5,8,8-Pentamethyl-2-Naphthyl)Propen-1 -Yl)Benzoic Acid is a high-purity synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key building block for the development of novel pharmaceutical compounds and functional materials. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new active ingredients with specific structural motifs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel Retinoid X Receptor (RXR) agonists and other nuclear receptor-targeting therapeutic agents.
• Agrochemical Research: Used in the development of new-generation plant growth regulators and selective herbicides due to its specific aromatic and aliphatic hybrid structure.
• Material Science: Acts as a monomer or functional additive in the synthesis of specialized polymers and liquid crystals, imparting unique thermal and optical properties.
• Chemical Biology: Employed as a molecular probe or tag in biochemical research to study protein-ligand interactions and cellular signaling pathways.
• Organic Synthesis: A versatile building block for constructing complex polycyclic frameworks and introducing specific functional groups in multi-step synthetic routes.

Basic Information

Item	Details
Product Name	(E)-3-(2-(5,6,7,8-Tetrahydro-3,5,5,8,8-Pentamethyl-2-Naphthyl)Propen-1 -Yl)Benzoic Acid
CAS No.	167413-64-1
Molecular Formula	C25H30O2
Molecular Weight	362.51 g/mol
Synonyms	Bexarotene Impurity; Bexarotene Related Compound; 3-(2-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)-1-propen-1-yl)benzoic acid; (E)-3-[2-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)propen-1-yl]benzoic acid; Targretin Impurity; LGD1069 Impurity; LG 100069 Impurity
EINECS	Contact for details

Quality Control

Our production of (E)-3-(2-(5,6,7,8-Tetrahydro-3,5,5,8,8-Pentamethyl-2-Naphthyl)Propen-1 -Yl)Benzoic Acid adheres to stringent quality management systems to ensure batch-to-batch consistency and reliability. The material undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with each shipment, supporting compliance in cGMP-aligned environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.