Description

(R)-Benzyl Methyl(1,2,3,4-Tetrahydroquinolin-3-Yl)Carbamate is a chiral, nitrogen-containing heterocyclic compound that serves as a sophisticated building block in advanced organic synthesis. Its value lies in its well-defined stereochemistry and functionalized tetrahydroquinoline scaffold, which is crucial for constructing molecules with high biological activity. This intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers developing active pharmaceutical ingredients (APIs), particularly in the areas of central nervous system (CNS) therapeutics and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for neurological and psychiatric disorders.
• Asymmetric Synthesis: Used as a precursor or ligand in catalytic asymmetric reactions to introduce stereogenic centers with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to explore and optimize the biological profile of tetrahydroquinoline-based compounds.
• API Development: Integral to the synthetic route of complex target molecules in preclinical and process chemistry stages.
• Fine Chemical Production: Serves as a specialized intermediate for custom synthesis and contract manufacturing organizations (CMOs).
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	(R)-Benzyl Methyl(1,2,3,4-Tetrahydroquinolin-3-Yl)Carbamate
CAS No.	166742-98-9
Molecular Formula	C19H22N2O2
Molecular Weight	310.39 g/mol
Synonyms	Carbamic acid, N-methyl-N-[(3R)-1,2,3,4-tetrahydro-3-quinolinyl]-, phenylmethyl ester; (R)-Benzyl N-Methyl-N-(1,2,3,4-tetrahydroquinolin-3-yl)carbamate; (3R)-N-Benzyloxycarbonyl-N-methyl-1,2,3,4-tetrahydroquinolin-3-amine; (R)-Cbz-Methyl-THQ-amine; (R)-Benzyl Methylcarbamate Tetrahydroquinoline Derivative
EINECS	Contact for details

Quality Control

Our (R)-Benzyl Methyl(1,2,3,4-Tetrahydroquinolin-3-Yl)Carbamate is produced under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including chiral purity assessment by HPLC, to meet the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Chiral Purity (HPLC)	≥98.0% ee
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.