Description

(R)-n-Methyl-1,2,3,4-Tetrahydroquinolin-3-Amine CAS NO 166742-75-2 is a chiral amine building block of significant importance in modern organic synthesis. This compound matters as a key intermediate for constructing complex molecules with defined stereochemistry, enabling the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Catalyst Ligand Precursor: Used to synthesize chiral ligands for metal-catalyzed reactions, enhancing enantioselectivity in industrial chemical processes.
• Agrochemical Synthesis: Serves as a building block for creating novel, stereochemically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: Employed in the manufacture of high-value, complex specialty chemicals where precise stereocontrol is required.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, exploring new synthetic routes and reaction mechanisms.

Basic Information

Product Name	(R)-n-Methyl-1,2,3,4-Tetrahydroquinolin-3-Amine
CAS No.	166742-75-2
Molecular Formula	C10H14N2
Molecular Weight	162.23 g/mol
Synonyms	(R)-N-Methyl-1,2,3,4-tetrahydroquinolin-3-amine; (R)-3-Amino-N-methyl-1,2,3,4-tetrahydroquinoline; (R)-N-Methyl-1,2,3,4-tetrahydro-3-quinolinamine; (3R)-N-Methyl-1,2,3,4-tetrahydroquinolin-3-amine; (R)-N-Methyl-1,2,3,4-tetrahydroquinolin-3-ylamine; (R)-MTQA; (R)-N-Methyl-Tetrahydroquinolin-3-Amine
EINECS	Contact for details

Quality Control

Our (R)-n-Methyl-1,2,3,4-Tetrahydroquinolin-3-Amine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including chiral purity (enantiomeric excess) and chemical purity, verified by advanced techniques such as HPLC, GC, and NMR. Certificates of Analysis (COA) are available for every batch upon request, detailing all relevant specifications to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (ee)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.