Description

Oxiraneacetic Acid, α-Amino-α-Methyl-, (R*,S*)- (9Ci) is a specialized chiral building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, which incorporates both an amino acid moiety and an oxirane (epoxide) ring, making it a versatile precursor for constructing complex, biologically active molecules. Pharmaceutical and agrochemical research and development teams need this high-value intermediate for the synthesis of novel active ingredients, particularly where stereochemistry is critical for efficacy.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for protease inhibitors and other enzyme-targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective herbicides, fungicides, and plant growth regulators.
• Peptidomimetic Chemistry: Serves as a constrained amino acid analog for designing peptide-like molecules with enhanced metabolic stability and bioavailability.
• Ligand and Catalyst Development: Employed in the synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Bioconjugation and Probe Synthesis: The reactive epoxide and amino groups facilitate its use in creating chemical probes for biochemical and diagnostic applications.
• Academic and Industrial R&D: A valuable reagent for methodological development in synthetic organic chemistry and medicinal chemistry programs.

Basic Information

Product Name	Oxiraneacetic Acid, α-Amino-α-Methyl-, (R*,S*)- (9Ci)
CAS No.	166318-68-9
Molecular Formula	C6H9NO3
Molecular Weight	143.14 g/mol
Synonyms	2-Amino-2-methyloxiran-2-ylacetic acid; (±)-2-(1-Amino-1-methylethyl)oxiranecarboxylic acid; α-Amino-α-methyloxiraneacetic acid; 2-Methyl-2-(oxiran-2-yl)alanine; (R*,S*)-2-Amino-2-methyl-3-oxiranepropanoic acid; Amino-methyl-oxirane acetic acid; Epoxy amino acid derivative
EINECS	Contact for details

Quality Control

Our Oxiraneacetic Acid, α-Amino-α-Methyl-, (R*,S*)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% (R*,S*)-racemate
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.