Description

2-Amino-3-Butenoic Acid Trifluoroacetate Salt is a high-purity, non-proteinogenic amino acid derivative, specifically the trifluoroacetate salt of the vinylglycine analog. This compound is a crucial chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel bioactive molecules and complex natural products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly enzyme inhibitors and mechanism-based inactivators.
• Biochemical Research: Used as a precursor or analog in studies of amino acid metabolism, enzyme mechanisms, and biosynthetic pathways.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients with specific biological activity.
• Peptide Mimetics: Incorporated into peptide chains to introduce conformational constraints or novel functional groups, enhancing stability and bioactivity.
• Asymmetric Synthesis: Employed as a starting material for the preparation of other non-natural amino acids and complex chiral molecules.
• Ligand and Catalyst Development: Used to create novel chelating agents or organocatalysts for stereoselective transformations.

Basic Information

Product Name	2-Amino-3-Butenoic Acid Trifluoroacetate Salt
CAS No.	166301-19-5
Molecular Formula	C6H8F3NO4
Molecular Weight	215.13 g/mol
Synonyms	2-Amino-3-butenoic acid trifluoroacetate; (2-Amino-3-butenoic acid) trifluoroacetate; Vinylglycine trifluoroacetate salt; 2-Amino-but-3-enoic acid trifluoroacetate; 3-Butenoic acid, 2-amino-, trifluoroacetate (1:1); 2-Amino-3-butenoic acid TFA salt; 2-Amino-3-butenoic acid trifluoroacetic acid salt
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Butenoic Acid Trifluoroacetate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.