Description

8-Chloro-3-Methoxy-5,6-Dihydro-11H-Benzo[5,6]-Cyclohepta[1,2-β]Pyridin-11- One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of proprietary drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes to develop new bioactive molecules.
• Active Pharmaceutical Ingredient (API) Development: A crucial precursor in the multi-step synthesis of complex APIs for clinical trials and commercial production.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Reference Standard: Can be supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	8-Chloro-3-Methoxy-5,6-Dihydro-11H-Benzo[5,6]-Cyclohepta[1,2-β]Pyridin-11- One
CAS No.	165739-70-8
Molecular Formula	C16H14ClNO2
Molecular Weight	287.74 g/mol
Synonyms	8-Chloro-3-methoxy-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-one; 11H-Benzo[5,6]cyclohepta[1,2-b]pyridin-11-one, 8-chloro-5,6-dihydro-3-methoxy-; Loratadine Related Compound; Desloratadine Intermediate; Tricyclic Pyridine Derivative
EINECS	Contact for details

Quality Control

Our 8-Chloro-3-Methoxy-5,6-Dihydro-11H-Benzo[5,6]-Cyclohepta[1,2-β]Pyridin-11- One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring the material is suitable for demanding pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.