Description

4-(Aminomethyl)-3-Chloro-Benzoic Acid is a high-purity, functionalized benzoic acid derivative characterized by its reactive aminomethyl and chloro substituents. This compound serves as a versatile and critical pharmaceutical intermediate and organic synthesis building block, enabling the construction of complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Peptide Mimetics & Linker Chemistry: The aminomethyl group facilitates its use in creating peptide analogs and as a spacer/linker in bioconjugation and prodrug development.
• Ligand & Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands for metal catalysis and molecular recognition.
• Polymer & Material Science: Incorporated into polymer backbones to impart specific functional properties for advanced material applications.
• Chemical Research & Development: A valuable reagent for medicinal chemistry and process chemistry research in both academic and industrial settings.

Basic Information

Product Name	4-(Aminomethyl)-3-Chloro-Benzoic Acid
CAS No.	165530-43-8
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	3-Chloro-4-(aminomethyl)benzoic Acid; 4-(Aminomethyl)-3-chlorobenzoic Acid; Benzoic acid, 4-(aminomethyl)-3-chloro-; 3-Chloro-4-carboxybenzylamine; 4-Carboxy-2-chlorobenzylamine; (3-Chloro-4-carboxyphenyl)methanamine; 2-Chloro-4-(aminomethyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)-3-Chloro-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.