Description

4-(T-Boc-Aminomethyl)-3-Chlorobenzoic Acid is a high-purity, protected amino acid derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures where precise control over functional groups is essential. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in peptide mimetics, linker chemistry, and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used in solid-phase peptide synthesis (SPPS) and the creation of peptide mimetics with modified backbones.
• Linker and Spacer Unit: Incorporates a protected amine and carboxylic acid for constructing bioconjugates, PROTACs, and antibody-drug conjugates (ADCs).
• Chemical Biology Probes: Serves as a precursor for synthesizing labeled compounds and molecular probes for biological target identification.
• Agrochemical Research: Intermediate in the development of new herbicides and plant growth regulators with specific activity.
• Material Science: Monomer for synthesizing specialized polymers and functionalized surfaces requiring specific chemical handles.

Basic Information

Product Name	4-(T-Boc-Aminomethyl)-3-Chlorobenzoic Acid
CAS No.	165528-69-8
Molecular Formula	C13H16ClNO4
Molecular Weight	285.72 g/mol
Synonyms	3-Chloro-4-[[(1,1-dimethylethoxy)carbonyl]amino]methyl]benzoic Acid; 4-[(tert-Butoxycarbonylamino)methyl]-3-chlorobenzoic Acid; 3-Chloro-4-((tert-butoxycarbonylamino)methyl)benzoic Acid; 4-(Boc-aminomethyl)-3-chlorobenzoic Acid; 4-(N-Boc-aminomethyl)-3-chlorobenzoic Acid; 3-Chloro-4-[(Boc-amino)methyl]benzoic Acid; 4-(tert-Butoxycarbonylaminomethyl)-3-chlorobenzoic Acid; 165528-69-8
EINECS	Contact for details

Quality Control

Our 4-(T-Boc-Aminomethyl)-3-Chlorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with exacting standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available for every lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.