Description

1,3-Dioxolane-4-Methanol, α,2,2-Trimethyl-, (αr,4S)- is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its stereochemically defined structure, which is crucial for constructing complex molecules with specific three-dimensional configurations. This compound is primarily needed by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure pesticides and herbicides, where specific stereochemistry can enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity in chemical reactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require precise stereochemical control.
• Academic and Industrial Research: A valuable tool for methodological development in organic chemistry and for exploring new synthetic pathways in process chemistry.
• Material Science: Potential monomer or modifier for creating polymers with specific chiral properties for advanced material applications.

Basic Information

Product Name	1,3-Dioxolane-4-Methanol, α,2,2-Trimethyl-, (αr,4S)-
CAS No.	165524-52-7
Molecular Formula	C7H14O3
Molecular Weight	146.18 g/mol
Synonyms	(4S)-α,2,2-Trimethyl-1,3-dioxolane-4-methanol; (S)-(-)-2,2-Dimethyl-α,1,3-dioxolan-4-ethanol; (S)-2,2-Dimethyl-α-(hydroxymethyl)-1,3-dioxolane-4-methanol; (S)-2,2-Dimethyl-1,3-dioxolane-4-methanol, α-methyl-; (S)-α,2,2-Trimethyl-1,3-dioxolane-4-methanol; (S)-Pantolactone derivative; Chiral dioxolane methanol; Chiral C7 dioxolane building block.
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Methanol, α,2,2-Trimethyl-, (αr,4S)- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and spectroscopic identification, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic and spectral data are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.