Description

1,2,3,4-Cyclopentanetetrol, 5-(Hydroxymethyl)-, 1,2-Dibenzoate, 1R-(1.Alpha.,2.Beta.,3.Alpha.,4.Alpha.,5.Beta.)- is a high-purity, stereochemically defined carbohydrate derivative and benzoate ester, serving as a critical chiral building block and advanced pharmaceutical intermediate for complex organic synthesis. Its precise stereochemistry and functional group array make it invaluable for constructing nucleoside analogs, antiviral agents, and other bioactive molecules where specific spatial orientation is paramount. This compound is essential for R&D and production teams in pharmaceutical, biotech, and fine chemical sectors requiring reliable, high-quality synthetic intermediates.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel nucleoside and nucleotide analogs for antiviral and anticancer research.
• Biochemical Research: Used as a scaffold or starting material for probing enzyme mechanisms and developing glycosidase inhibitors.
• Asymmetric Synthesis: Serves as a chiral pool reagent or auxiliary for constructing complex natural products and active pharmaceutical ingredients (APIs).
• Carbohydrate Chemistry: A valuable substrate for studying and developing new glycosylation and protection/deprotection methodologies.
• Process Chemistry Development: Employed in route scouting and optimization for scalable manufacturing of stereochemically pure compounds.
• Reference Standard: Used as an analytical standard for quality control and method validation in pharmaceutical development.

Basic Information

Product Name	1,2,3,4-Cyclopentanetetrol, 5-(Hydroxymethyl)-, 1,2-Dibenzoate, 1R-(1.Alpha.,2.Beta.,3.Alpha.,4.Alpha.,5.Beta.)-
CAS No.	165375-22-4
Molecular Formula	C20H20O8
Molecular Weight	388.37 g/mol
Synonyms	(1R,2S,3R,4R,5S)-5-(Hydroxymethyl)cyclopentane-1,2,3,4-tetrol 1,2-Dibenzoate; 1,2-Di-O-benzoyl-5-C-(hydroxymethyl)-1,2,3,4-cyclopentanetetrol (1R,2S,3R,4R,5S)-; 1,2-Di-O-benzoyl-5-C-(hydroxymethyl)-1,2,3,4-cyclopentanetetrol; 1,2-Di-O-benzoyl-5-C-(hydroxymethyl)-1,2,3,4-cyclopentanetetrol (1R,2S,3R,4R,5S)-; 1,2-Di-O-benzoyl-5-C-(hydroxymethyl)-1,2,3,4-cyclopentanetetrol (1R,2S,3R,4R,5S)-; 1,2-Di-O-benzoyl-5-C-(hydroxymethyl)-1,2,3,4-cyclopentanetetrol (1R,2S,3R,4R,5S)-; 1,2-Di-O-benzoyl-5-C-(hydroxymethyl)-1,2,3,4-cyclopentanetetrol (1R,2S,3R,4R,5S)-; 1,2-Di-O-benzoyl-5-C-(hydroxymethyl)-1,2,3,4-cyclopentanetetrol (1R,2S,3R,4R,5S)-
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Cyclopentanetetrol, 5-(Hydroxymethyl)-, 1,2-Dibenzoate, 1R-(1.Alpha.,2.Beta.,3.Alpha.,4.Alpha.,5.Beta.)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.