Description

4-Benzyloxy-2-Bromonitrobenzene is a high-purity brominated nitroaromatic compound, serving as a versatile and critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which allows for selective functionalization, making it indispensable for creating complex chemical architectures. This intermediate is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the bromo and nitro groups enable further coupling reactions.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and photoactive polymers due to its electron-withdrawing nitro group.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses producing bespoke organic compounds for client R&D projects.
• Academic and Industrial R&D: Essential for methodological studies in organic chemistry, including new palladium-catalyzed cross-coupling and nucleophilic aromatic substitution reactions.

Basic Information

Product Name	4-Benzyloxy-2-Bromonitrobenzene
CAS No.	165190-62-5
Molecular Formula	C₁₃H₁₀BrNO₃
Molecular Weight	308.13 g/mol
Synonyms	2-Bromo-4-(phenylmethoxy)-1-nitrobenzene; 1-Benzyloxy-2-bromo-5-nitrobenzene; 4-(Benzyloxy)-2-bromonitrobenzene; 2-Bromo-4-benzyloxynitrobenzene; 2-Bromo-1-nitro-4-(phenylmethoxy)benzene; 4-Benzyloxy-2-bromo-1-nitrobenzene; 1-Nitro-2-bromo-4-benzyloxybenzene; Benzene, 2-bromo-1-nitro-4-(phenylmethoxy)-
EINECS	Contact for details

Quality Control

Every batch of 4-Benzyloxy-2-Bromonitrobenzene is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, and custom specifications can be supported for cGMP or other regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.