Description

(6-Fluoroquinolin-2-Yl)Methanol is a high-value fluorinated quinoline derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate the unique properties of the fluorinated quinoline scaffold into their target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in antimicrobial, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in developing advanced pesticides and herbicides where the fluorine atom enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science: Intermediate in the synthesis of organic electronic materials, such as OLEDs and semiconductors, leveraging the quinoline core's electron-transport properties.
• Fluorine Chemistry Studies: A valuable substrate for investigating new fluorination reactions and studying structure-activity relationships (SAR).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity fluorinated intermediates.

Basic Information

Product Name	(6-Fluoroquinolin-2-Yl)Methanol
CAS No.	165111-37-5
Molecular Formula	C₁₀H₈FNO
Molecular Weight	177.18 g/mol
Synonyms	2-(Hydroxymethyl)-6-fluoroquinoline; 6-Fluoro-2-quinolinemethanol; (6-Fluoro-2-quinolyl)methanol; 6-Fluoroquinoline-2-methanol; 6-Fluoro-2-(hydroxymethyl)quinoline; 165111-37-5; 2-Quinolinemethanol, 6-fluoro-
EINECS	Contact for details

Quality Control

Our (6-Fluoroquinolin-2-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.