Description

4-(Aminomethyl)-n-Methylbenzamide is a specialized aromatic amide building block featuring both an aminomethyl and an N-methylamide functional group. This unique bifunctional structure makes it a valuable intermediate for synthesizing more complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis. The compound's reactivity allows for selective modifications, enabling the creation of targeted libraries for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its aromatic core for bioactive compound design.
• Peptidomimetics & Bioactive Molecule Development: Serves as a constrained scaffold or spacer in the design of peptide analogs and other bioactive molecules to improve metabolic stability and binding affinity.
• Chemical Biology & Proteomics: Employed as a linker or functional handle in the creation of chemical probes and affinity tags for studying protein function and interactions.
• Material Science Research: Investigated as a monomer or cross-linking agent in the development of specialized polymers with tailored thermal or mechanical properties.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) serving the life sciences industry.

Basic Information

Product Name	4-(Aminomethyl)-n-Methylbenzamide
CAS No.	164648-64-0
Molecular Formula	C9H12N2O
Molecular Weight	164.20 g/mol
Synonyms	4-(Aminomethyl)-N-methylbenzamide; N-Methyl-4-(aminomethyl)benzamide; 4-(Aminomethyl)-N-methyl-benzenecarboxamide; Benzenecarboxamide, 4-(aminomethyl)-N-methyl-; p-(Aminomethyl)-N-methylbenzamide; 4-Carbamoylmethylbenzylamine (N-methyl); 1-Methyl-3-(4-aminomethylphenyl)urea precursor
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)-n-Methylbenzamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.