Description

5-(4-Fluorophenyl)-2-Fluorobenzoic Acid is a high-purity fluorinated aromatic carboxylic acid building block. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is essential for medicinal chemists and process development scientists working on active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, leveraging the stability of the fluorinated aromatic system.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for display technologies.
• Organic Electronic Materials: Employed in the development of organic semiconductors and charge-transport materials.
• Chemical Research & Development: A versatile reagent for introducing fluorinated biphenyl motifs into more complex molecular architectures in academic and industrial labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP guidelines.

Basic Information

Product Name	5-(4-Fluorophenyl)-2-Fluorobenzoic Acid
CAS No.	164164-26-5
Molecular Formula	C₁₃H₈F₂O₂
Molecular Weight	234.20 g/mol
Synonyms	2-Fluoro-5-(4-fluorophenyl)benzoic Acid; 5-(4-Fluorophenyl)-2-fluorobenzoic Acid; [1,1'-Biphenyl]-2-carboxylic acid, 2'-fluoro-5-fluoro-; 2'-Fluoro-5-fluorobiphenyl-2-carboxylic Acid; 2-Fluoro-5-(4-fluorophenyl)benzoic acid; 5-(4-Fluorophenyl)-2-fluorobenzoic acid; 164164-26-5; Biphenyl-2-carboxylic acid, 2'-fluoro-5-fluoro-
EINECS	Contact for details

Quality Control

Our 5-(4-Fluorophenyl)-2-Fluorobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.