Description

3-(2-Iodoethoxy)Prop-1-Yne is a specialized organic building block featuring both an iodoalkyl ether and a terminal alkyne functional group. This unique bifunctional structure makes it a valuable intermediate for advanced organic synthesis, particularly in click chemistry and cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), especially for targeted drug delivery systems.
• Click Chemistry Reagent: The terminal alkyne group enables efficient Huisgen 1,3-dipolar cycloaddition (copper-catalyzed azide-alkyne cycloaddition, CuAAC) for bioconjugation and polymer functionalization.
• Cross-Coupling Reactions: The iodine atom acts as a handle for palladium-catalyzed cross-coupling reactions (e.g., Sonogashira, Suzuki-Miyaura) to form new carbon-carbon bonds.
• Ligand and Catalyst Synthesis: Used in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Polymer and Material Science: Employed as a monomer or cross-linking agent for creating functional polymers, dendrimers, and advanced materials with tailored properties.
• Agrochemical Research: Acts as a building block for synthesizing new crop protection agents and herbicides.

Basic Information

Product Name	3-(2-Iodoethoxy)Prop-1-Yne
CAS No.	164118-56-3
Molecular Formula	C5H7IO
Molecular Weight	210.01 g/mol
Synonyms	2-(2-Propynyloxy)ethyl Iodide; 1-Iodo-2-(2-propynyloxy)ethane; 3-(2-Iodoethoxy)-1-propyne; Propargyl 2-iodoethyl ether; 2-(Prop-2-yn-1-yloxy)ethyl Iodide
EINECS	Contact for details

Quality Control

Our 3-(2-Iodoethoxy)Prop-1-Yne is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.