Description

H-Ile-Nhnh2 CAS NO 163979-02-0 is a high-purity, protected amino acid derivative specifically designed for advanced peptide synthesis and pharmaceutical research. This compound serves as a critical building block, enabling the precise construction of complex peptide chains with the isoleucine residue while protecting the reactive amine group. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for developing novel therapeutic agents and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the solid-phase and solution-phase synthesis of therapeutic peptides and peptidomimetics.
• Bioconjugation: Used for site-specific labeling and modification of proteins and antibodies in drug development.
• Proteomics Research: Employed in the study of protein structure, function, and interactions within academic and industrial R&D labs.
• Combinatorial Chemistry: A valuable component in libraries for high-throughput screening to discover new drug candidates.
• Agrochemical Development: Utilized in the research and synthesis of novel bioactive peptides for crop protection.
• Diagnostic Reagent Synthesis: Acts as a building block for peptide-based diagnostic markers and probes.

Basic Information

Product Name	H-Ile-Nhnh2
CAS No.	163979-02-0
Molecular Formula	C9H19N3O2
Molecular Weight	201.27 g/mol
Synonyms	N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine hydrazide; Fmoc-Ile-NHNH2; Fmoc-L-isoleucine hydrazide; (2S,3S)-2-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-methylpentanoic acid hydrazide; Fmoc-Ile-OH hydrazide; Nα-Fmoc-isoleucine hydrazide; Protected isoleucine hydrazide; Peptide synthesis building block
EINECS	Contact for details

Quality Control

Our H-Ile-Nhnh2 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and production. Each lot undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.