Description

(1R,2R)-Ethyl 2-((R)-1-Phenylethylamino)Cyclopentanecarboxylate Hydrochloride is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its precise stereochemistry makes it a valuable building block for the development of enantiomerically pure pharmaceuticals and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or resolving agent in stereoselective synthesis to control the configuration of new stereocenters.
• Agrochemical Research: Used in the development of enantiomerically pure pesticides and herbicides where specific stereochemistry is crucial for activity and environmental safety.
• Catalyst Ligand Precursor: Serves as a starting material for the synthesis of novel chiral ligands used in homogeneous catalysis.
• Academic & Process Chemistry: Utilized in university and industrial R&D for method development and scaling up chiral synthetic routes.
• Fine Chemical Production: Integral in the manufacture of specialty chemicals requiring high enantiomeric purity for flavors, fragrances, or advanced materials.

Basic Information

Product Name	(1R,2R)-Ethyl 2-((R)-1-Phenylethylamino)Cyclopentanecarboxylate Hydrochloride
CAS No.	163877-11-0
Molecular Formula	C16H24ClNO2
Molecular Weight	297.82 g/mol
Synonyms	(1R,2R)-Ethyl 2-[(1R)-1-Phenylethylamino]cyclopentanecarboxylate hydrochloride; (1R,2R)-2-[(R)-1-Phenylethylamino]cyclopentanecarboxylic acid ethyl ester hydrochloride; Ethyl (1R,2R)-2-[(1R)-1-phenylethylamino]cyclopentanecarboxylate hydrochloride; (1R,2R)-Ethyl 2-((R)-α-Methylbenzylamino)cyclopentanecarboxylate HCl; (1R,2R)-REL-2-[(1R)-1-Phenylethylamino]cyclopentanecarboxylic Acid Ethyl Ester Hydrochloride; CAS 163877-11-0
EINECS	Contact for details

Quality Control

Our (1R,2R)-Ethyl 2-((R)-1-Phenylethylamino)Cyclopentanecarboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.