Description

Phenol, 2-Amino-3,5-Difluoro- (9Ci) is a fluorinated aniline derivative, a high-value organic intermediate prized for its unique substitution pattern. This compound is critical for introducing both amino and fluorine functionalities into complex molecular architectures, enabling precise tuning of electronic and steric properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients, as well as by manufacturers of advanced materials and specialty dyes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in fluorinated bioactive molecules targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where fluorine atoms enhance metabolic stability and bioavailability.
• Advanced Material Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers, liquid crystals, and electronic materials.
• Dye and Pigment Manufacturing: Employed in the synthesis of high-performance, light-fast fluorinated dyes and pigments for specialized applications.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in organic synthesis, medicinal chemistry, and fluorine chemistry.
• Ligand Synthesis for Catalysis: Used to prepare fluorinated ligands for transition metal catalysts, improving selectivity and efficiency in coupling reactions.

Basic Information

Product Name	Phenol, 2-Amino-3,5-Difluoro- (9Ci)
CAS No.	163733-98-0
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	2-Amino-3,5-difluorophenol; 3,5-Difluoro-2-aminophenol; 2-Amino-3,5-difluoro-1-hydroxybenzene; 3,5-Difluoro-2-hydroxyaniline; 2-Hydroxy-3,5-difluoroaniline; 1-Hydroxy-2-amino-3,5-difluorobenzene; 2-Amino-3,5-difluorophenol (9CI)
EINECS	Contact for details

Quality Control

Our production of 2-Amino-3,5-difluorophenol adheres to stringent quality management protocols. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting customer specifications. Certificates of Analysis (COA) detailing all test results are provided with every shipment to guarantee traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	Off-white to light tan crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.