Description

1,3-Dioxolane-4,5-Dimethanol, α4,α4,α5,α5-Tetrakis[4-(1,1-Dimethylethyl)Phenyl]-2,2-Dimethyl-, (4R,5R)- is a high-value, stereochemically defined chiral building block and ligand precursor. Its complex, sterically hindered structure with multiple tert-butylphenyl groups makes it a critical component for advanced applications in asymmetric synthesis and materials science. This compound is primarily sought after by research and development teams in the pharmaceutical and specialty chemical industries for creating novel catalysts and high-performance polymers.

Application

• Chiral Ligand Synthesis: Serves as a sophisticated precursor for the development of novel asymmetric catalysts used in enantioselective transformations.
• Pharmaceutical Intermediates: Utilized in the research and synthesis of complex, stereospecific active pharmaceutical ingredients (APIs) requiring high enantiomeric purity.
• Advanced Material Monomers: Acts as a building block for specialty polymers and resins where its bulky, rigid structure can impart unique thermal and mechanical properties.
• Organometallic Chemistry: Employed in the preparation of metal-organic frameworks (MOFs) or coordination complexes due to its multiple potential coordination sites.
• Fine Chemical Synthesis: Used as a key intermediate in multi-step synthetic routes for high-value agrochemicals, flavors, and fragrances.
• Academic & Industrial R&D: A valuable tool for chemists exploring new reaction methodologies and catalytic systems in both university and corporate laboratory settings.

Basic Information

Product Name	1,3-Dioxolane-4,5-Dimethanol, α4,α4,α5,α5-Tetrakis[4-(1,1-Dimethylethyl)Phenyl]-2,2-Dimethyl-, (4R,5R)-
CAS No.	163726-72-5
Molecular Formula	C48H62O4
Molecular Weight	702.99 g/mol
Synonyms	(4R,5R)-2,2-Dimethyl-α,α,α',α'-tetrakis(4-tert-butylphenyl)-1,3-dioxolane-4,5-dimethanol; (4R,5R)-4,5-Bis(hydroxymethyl)-2,2-dimethyl-α,α,α',α'-tetrakis(4-tert-butylphenyl)-1,3-dioxolane; TADDOL Derivative (tert-butyl substituted); (R,R)-TADDOL-(4-tert-butylphenyl); Chiral 1,3-Dioxolane-4,5-dimethanol Derivative; Asymmetric Dioxolane Ligand Precursor
EINECS	Contact for details

Quality Control

Our production of this advanced chiral compound adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Certificates of Analysis (COA) are provided with each shipment, detailing key parameters such as chiral purity (enantiomeric excess), chemical purity by HPLC, and identity confirmation. We support cGMP and ISO 9001 compliant manufacturing environments for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.