Description

3-Pyridin-2-Yl-[1,2,4]Oxadiazole-5-Carboxylic Acid Ethyl Ester CAS NO 163719-76-4 is a high-purity heterocyclic building block and pharmaceutical intermediate of significant commercial interest. This compound is valued for its unique molecular architecture, which combines pyridine and oxadiazole moieties, making it a versatile scaffold in modern synthetic chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

This specialized intermediate serves as a critical component in advanced chemical synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A key building block for the research and development of new drug candidates, particularly in areas like kinase inhibitors and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Chemical Research & Development: Serves as a versatile precursor for synthesizing complex heterocyclic libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science: Potential use as a monomer or functional additive in the development of advanced polymers and functional materials.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	3-Pyridin-2-Yl-[1,2,4]Oxadiazole-5-Carboxylic Acid Ethyl Ester
CAS No.	163719-76-4
Molecular Formula	C11H10N4O3
Molecular Weight	246.22 g/mol
Synonyms	Ethyl 3-(pyridin-2-yl)-1,2,4-oxadiazole-5-carboxylate; 2-Pyridyl-1,2,4-oxadiazole-5-carboxylic Acid Ethyl Ester; 5-(Ethoxycarbonyl)-3-(2-pyridyl)-1,2,4-oxadiazole; 3-(2-Pyridinyl)-1,2,4-oxadiazole-5-carboxylic Acid Ethyl Ester; 1,2,4-Oxadiazole-5-carboxylic acid, 3-(2-pyridinyl)-, ethyl ester; CAS 163719-76-4
EINECS	Contact for details

Quality Control

Our production of 3-Pyridin-2-Yl-[1,2,4]Oxadiazole-5-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects with material suitable for research use through to cGMP-grade manufacturing, with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed immediately after use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.