Description

D-Glucitol, 2-(Acetylamino)-2-Deoxy-5,6-o-(1-Methylethylidene)-3-o-(Phenylmethyl)-, 1,4-Diacetate is a sophisticated, multi-protected carbohydrate derivative, specifically engineered as a high-value pharmaceutical intermediate and chiral building block for complex organic synthesis. Its carefully designed structure, featuring acetylamino, isopropylidene, benzyl, and acetyl protecting groups, provides precise control over reactivity and stereochemistry. This compound is essential for researchers and manufacturers in medicinal chemistry and process development who require advanced intermediates for the synthesis of novel therapeutics and bioactive molecules.

Application

• Key Intermediate in Glycobiology & Medicinal Chemistry: Serves as a crucial precursor for the synthesis of complex glycosidase inhibitors, neuraminidase inhibitors, and other carbohydrate-based pharmaceuticals.
• Chiral Pool Synthesis: Utilized as a versatile chiral starting material or scaffold for the asymmetric synthesis of natural products and active pharmaceutical ingredients (APIs).
• Process Research & Development (R&D): Employed in route scouting and optimization for the commercial-scale production of high-value specialty chemicals and drug candidates.
• Academic & Industrial Research: Used in studies exploring glycosylation reactions, carbohydrate chemistry, and the development of new synthetic methodologies.
• Precursor for Protected Sugar Analogues: Acts as a building block for further functionalization to create a library of selectively protected sugar derivatives for screening and discovery.

Basic Information

Product Name	D-Glucitol, 2-(Acetylamino)-2-Deoxy-5,6-o-(1-Methylethylidene)-3-o-(Phenylmethyl)-, 1,4-Diacetate
CAS No.	163707-55-9
Molecular Formula	C22H31NO8
Molecular Weight	437.49 g/mol
Synonyms	1,4-Di-O-acetyl-2-acetamido-3-O-benzyl-5,6-O-isopropylidene-2-deoxy-D-glucitol; 2-Acetamido-3-O-benzyl-5,6-O-isopropylidene-2-deoxy-D-glucitol 1,4-diacetate; 2-Deoxy-2-(acetylamino)-3-O-benzyl-5,6-O-(1-methylethylidene)-D-glucitol 1,4-diacetate; Protected Glucitol Derivative; Benzyl-Protected Glucitol Intermediate; Isopropylidene Acetal of D-Glucitol Derivative
EINECS	Contact for details

Quality Control

This high-purity synthetic intermediate is produced under strict quality management systems. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and MS to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; the container should be kept tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.