Description

7-Azabicyclo[2.2.1]Heptane-2-Carbonitrile,7-Methyl-,(1R,2R,4S)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic nitrile building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional scaffold and functional handles make it a valuable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and catalyst development.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in neurological and antiviral research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and library synthesis to explore new chemical space due to its constrained geometry.
• Ligand and Catalyst Synthesis: Serves as a precursor for sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Intermediate in the development of new generation herbicides and insecticides with specific stereochemical requirements.
• Chemical Biology Probes: Utilized in the design of molecular probes to study enzyme function and biological pathways.
• Academic & Industrial R&D: Fundamental research compound in synthetic methodology development and heterocyclic chemistry.

Basic Information

Product Name	7-Azabicyclo[2.2.1]Heptane-2-Carbonitrile,7-Methyl-,(1R,2R,4S)-Rel-(9Ci)
CAS No.	163517-79-1
Molecular Formula	C8H12N2
Molecular Weight	136.20 g/mol
Synonyms	(1R,2R,4S)-7-Methyl-7-azabicyclo[2.2.1]heptane-2-carbonitrile; rel-(1R,2R,4S)-7-Methyl-7-azabicyclo[2.2.1]heptane-2-carbonitrile; 7-Methyl-7-azabicyclo[2.2.1]heptane-2-carbonitrile, (1R,2R,4S)-rel-; 7-Azabicyclo[2.2.1]heptane-2-carbonitrile, 7-methyl-, (1R,2R,4S)-rel-; Bicyclic Nitrile Intermediate 163517-79-1
EINECS	Contact for details

Quality Control

Every batch of our 7-Azabicyclo[2.2.1]Heptane-2-Carbonitrile,7-Methyl-,(1R,2R,4S)-Rel-(9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure high chemical and chiral purity, meeting the exacting standards required for research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.