Description

Ethyl 4-Amino-2-Methylquinoline-3-Carboxylate is a high-purity, versatile quinoline derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various quinoline-based drug candidates, including potential antimalarial and anticancer agents.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging the bioactive quinoline scaffold.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for the preparation of electron-transport or emissive layer materials in electronic displays.
• Coordination Chemistry & Ligand Synthesis: Utilized to create complexing agents or ligands for catalytic and metal-organic framework (MOF) applications.
• Dye & Pigment Industry: Acts as an intermediate for the synthesis of specialized quinoline dyes and colorants.
• Academic & Contract Research: Employed in medicinal chemistry and material science research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	Ethyl 4-Amino-2-Methylquinoline-3-Carboxylate
CAS No.	163455-37-6
Molecular Formula	C₁₃H₁₄N₂O₂
Molecular Weight	230.26 g/mol
Synonyms	4-Amino-2-methylquinoline-3-carboxylic acid ethyl ester; Ethyl 4-amino-2-methyl-3-quinolinecarboxylate; 2-Methyl-4-aminoquinoline-3-carboxylic acid ethyl ester; 3-Quinolinecarboxylic acid, 4-amino-2-methyl-, ethyl ester; 4-Amino-2-methylquinoline-3-carboxylate ethyl ester; Ethyl α-methyl-4-aminoquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 4-Amino-2-Methylquinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.