Description

2-Chloro-4-Methylthiobutanoicacid is a specialized sulfur-containing organic acid chloride derivative, serving as a critical chiral building block and intermediate in advanced synthetic chemistry. Its unique structure, featuring both chloro and methylthio functional groups, makes it invaluable for constructing complex molecules with high stereochemical control. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of chiral drugs, particularly those targeting cardiovascular and central nervous system disorders.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with specific modes of action.
• Peptide Mimetics & Conjugation: Used in the preparation of peptide analogs and for bioconjugation strategies in drug discovery.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis.
• Material Science Research: Intermediate in the development of functionalized polymers and advanced organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions.

Basic Information

Product Name	2-Chloro-4-Methylthiobutanoicacid
CAS No.	163401-68-1
Molecular Formula	C5H9ClO2S
Molecular Weight	168.64 g/mol
Synonyms	2-Chloro-4-(methylthio)butanoic Acid; 4-(Methylthio)-2-chlorobutanoic Acid; (RS)-2-Chloro-4-methylthiobutanoic Acid; (±)-2-Chloro-4-(methylthio)butyric Acid; 2-Chloro-4-methylmercaptobutyric Acid; 2-Chloro-4-(methylsulfanyl)butanoic Acid; Butanoic acid, 2-chloro-4-(methylthio)-; α-Chloro-γ-(methylthio)butyric Acid
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methylthiobutanoicacid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming specifications for identity, purity (typically ≥97% by HPLC), and impurity profiles. We support development and commercial projects with consistent quality, from laboratory to pilot and production scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen to prevent degradation. Keep away from strong bases, oxidizing agents, and heat sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.