Description

Phenylalanine, 4-Nitro-, Ethyl Ester, Monohydrochloride is a chemically modified derivative of the amino acid phenylalanine, serving as a crucial chiral building block and synthetic intermediate in advanced organic synthesis. Its value lies in providing a protected, activated form of phenylalanine with a nitro group for further functionalization, enabling the efficient production of complex molecules. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of peptide-based therapeutics, enzyme inhibitors, and other bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and production of novel active pharmaceutical ingredients (APIs), particularly for peptide drugs and enzyme inhibitors.
• Biochemical Research: Used as a specialized substrate or precursor in enzymatic studies and metabolic pathway investigations.
• Peptide Synthesis: Serves as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis for creating custom peptide sequences.
• Organic Synthesis: Acts as a versatile building block for the synthesis of more complex, nitrogen-containing heterocycles and fine chemicals.
• Agrochemical Development: Potential intermediate in the synthesis of advanced, targeted pesticides and herbicides.

Basic Information

Product Name	Phenylalanine, 4-Nitro-, Ethyl Ester, Monohydrochloride
CAS No.	163251-51-2
Molecular Formula	C11H14N2O4 • HCl
Molecular Weight	274.70 g/mol
Synonyms	4-Nitro-L-phenylalanine ethyl ester hydrochloride; L-4-Nitrophenylalanine ethyl ester hydrochloride; Ethyl (2S)-2-amino-3-(4-nitrophenyl)propanoate hydrochloride; (S)-2-Amino-3-(4-nitrophenyl)propionic acid ethyl ester hydrochloride; 4-NO2-Phe-OEt • HCl; 4-Nitrophenylalanine ethyl ester HCl; p-Nitrophenylalanine ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Phenylalanine, 4-Nitro-, Ethyl Ester, Monohydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.