Description

3-(5-Nitro-Pyridin-2-Ylethynyl)-Quinoline is a specialized organic compound featuring a quinoline core linked to a nitropyridine moiety via an ethynyl bridge, making it a valuable advanced pharmaceutical intermediate and key building block in medicinal chemistry. Its unique conjugated structure is critical for the synthesis of complex molecules targeting specific biological pathways. This high-purity intermediate is primarily utilized by research institutions and pharmaceutical R&D departments engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of potential drug candidates, particularly in oncology and antiviral research.
• Organic Synthesis Building Block: Used in cross-coupling reactions and as a scaffold for constructing complex heterocyclic compounds in medicinal chemistry.
• Agrochemical Research: Employed in the development of new active ingredients for crop protection products.
• Material Science: Investigated for use in the creation of organic semiconductors and light-emitting materials due to its extended π-conjugation system.
• Biochemical Probe Development: Utilized in designing molecular probes for studying enzyme inhibition and receptor binding.

Basic Information

Item	Details
Product Name	3-(5-Nitro-Pyridin-2-Ylethynyl)-Quinoline
CAS No.	163085-38-9
Molecular Formula	C16H9N3O2
Molecular Weight	275.26 g/mol
Synonyms	3-[(5-Nitro-2-pyridinyl)ethynyl]quinoline; Quinoline, 3-[(5-nitro-2-pyridinyl)ethynyl]-; 3-(5-Nitropyridin-2-ylethynyl)quinoline; 3-(5-Nitro-2-pyridylethynyl)quinoline; 2-(Quinolin-3-ylethynyl)-5-nitropyridine
EINECS	Contact for details

Quality Control

Every batch of 3-(5-Nitro-Pyridin-2-Ylethynyl)-Quinoline is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.