Description

1-(Thien-2-Yl)Cyclopropanecarboxylic Acid is a high-value heterocyclic building block featuring a fused thiophene and cyclopropane carboxylic acid structure. This compound is essential for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging its unique bicyclic structure for biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialized polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalytic processes.
• Academic and Industrial Research: A versatile building block for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-(Thien-2-Yl)Cyclopropanecarboxylic Acid
CAS No.	162959-94-6
Molecular Formula	C8H8O2S
Molecular Weight	168.21 g/mol
Synonyms	1-(2-Thienyl)cyclopropanecarboxylic acid; 1-(Thiophen-2-yl)cyclopropanecarboxylic acid; 2-Cyclopropylcarboxylic acid thiophene; 1-(2-Thienyl)cyclopropanecarboxylic acid; Cyclopropanecarboxylic acid, 1-(2-thienyl)-; 1-Thiophen-2-yl-cyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(Thien-2-Yl)Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.