Description

(S)-(-)-n-Boc-2-Amino-1,5-Pentanediol is a high-purity, chiral building block essential for advanced organic synthesis. This compound is a key intermediate in the production of complex pharmaceuticals, particularly for constructing peptide mimetics and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of protease inhibitors, antiviral drugs, and other small molecule therapeutics.
• Peptidomimetic Chemistry: Used to introduce chiral amino diol motifs into peptide backbones to enhance stability and biological activity.
• Asymmetric Synthesis: Serves as a versatile starting material or auxiliary in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for the amine functionality in multi-step synthetic sequences.
• Ligand and Catalyst Development: Potential precursor for chiral ligands used in transition metal catalysis.
• Academic and Industrial R&D: Employed in medicinal chemistry programs for lead optimization and structure-activity relationship (SAR) studies.

Basic Information

Product Name	(S)-(-)-n-Boc-2-Amino-1,5-Pentanediol
CAS No.	162955-48-8
Molecular Formula	C₁₀H₂₁NO₄
Molecular Weight	219.28 g/mol
Synonyms	(S)-2-[(tert-Butoxycarbonyl)amino]-1,5-pentanediol; (2S)-2-[[(1,1-Dimethylethoxy)carbonyl]amino]-1,5-pentanediol; (S)-2-(Boc-amino)-1,5-pentanediol; (S)-N-Boc-2-Amino-1,5-pentanediol; (S)-N-Boc-2-Amino-1,5-dihydroxypentane; (S)-2-(tert-Butoxycarbonylamino)-1,5-pentanediol; Boc-Aadiol(S); (S)-Boc-Aadiol
EINECS	Contact for details

Quality Control

Our (S)-(-)-n-Boc-2-Amino-1,5-Pentanediol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.