Description

n-Phenyl-Tetrahydrofuran-3-Ylamine Hydrochloride is a high-purity organic salt compound, serving as a critical building block in advanced pharmaceutical synthesis and fine chemical research. Its value lies in its role as a versatile chiral amine intermediate, enabling the construction of complex molecular architectures with high stereochemical control. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides where specific stereochemistry is required for biological activity.
• Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, dyes, and functional polymers.
• Academic & Contract Research: Valuable reagent for methodological development and discovery chemistry in university and CRO laboratories.
• Process Chemistry: Scalable intermediate for optimizing synthetic routes toward target molecules in kilo-lab and pilot plant settings.

Basic Information

Product Name	n-Phenyl-Tetrahydrofuran-3-Ylamine Hydrochloride
CAS No.	162851-41-4
Molecular Formula	C₁₀H₁₄ClNO
Molecular Weight	199.68 g/mol
Synonyms	3-(Phenylamino)tetrahydrofuran hydrochloride; 3-Anilinooxolane hydrochloride; Tetrahydro-3-(phenylamino)furan hydrochloride; N-Phenyl-3-aminotetrahydrofuran HCl; 3-(N-Phenylamino)tetrahydrofuran hydrochloride; N-Phenyltetrahydrofuran-3-amine hydrochloride; 1-Phenyl-1,4-diazepane hydrochloride (common mis-assignment check); Furan, tetrahydro-3-(phenylamino)-, hydrochloride
EINECS	Contact for details

Quality Control

Our n-Phenyl-Tetrahydrofuran-3-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can compromise product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.