Description

D-Glucose, 2,3,4,5,6-Penta-o-Methyl-, Cyclic (S)-1,1-Binaphthalene-2,2-Diyl Dithioacetal is a sophisticated chiral building block and ligand precursor, distinguished by its fully protected glucose scaffold and a binaphthyl-derived dithioacetal moiety. This compound matters for its role in asymmetric synthesis, where it serves as a key intermediate for constructing complex molecular architectures with high stereochemical control. It is primarily needed by research and development laboratories in the pharmaceutical and fine chemical sectors for developing novel catalysts, chiral auxiliaries, and advanced materials.

Application

• Chiral Ligand Synthesis: A crucial precursor for developing novel, enantioselective catalysts used in asymmetric hydrogenation, oxidation, and C-C bond-forming reactions.
• Pharmaceutical Intermediate: Serves as a high-value building block in the multi-step synthesis of optically active drug candidates and active pharmaceutical ingredients (APIs).
• Glycochemistry Research: Used in advanced studies of carbohydrate chemistry and the development of glycosylation methodologies with protected sugar derivatives.
• Material Science: Potential application in the design of chiral stationary phases for chromatographic separation or chiral molecular recognition systems.
• Academic & Industrial R&D: A specialized reagent for investigating new methodologies in stereoselective synthesis and organocatalysis.

Basic Information

Item	Details
Product Name	D-Glucose, 2,3,4,5,6-Penta-o-Methyl-, Cyclic (S)-1,1-Binaphthalene-2,2-Diyl Dithioacetal
CAS No.	162825-41-4
Molecular Formula	C39H40O5S2
Molecular Weight	652.86 g/mol
Synonyms	(S)-1,1'-Binaphthalene-2,2'-diyl D-Glucose Pentamethyl Dithioacetal; Cyclic (S)-BINOL Dithioacetal of 2,3,4,5,6-Penta-O-methyl-D-glucopyranose; (S)-BINOL-Glucose Dithioacetal; Penta-O-methyl-D-glucopyranose cyclic (S)-1,1'-binaphthyl-2,2'-diyl dithioacetal; (S)-2,2'-Bis(2,3,4,5,6-penta-O-methyl-D-glucopyranos-1-ylthio)-1,1'-binaphthyl; Chiral Glucose-BINOL Dithioacetal Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specific results for chiral purity (enantiomeric excess), assay, and impurity profiles are available upon request. We adhere to a cGMP-compliant quality management system for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.