Description

n-Boc-N''-(3-Hydroxybenzyl)Hydrazine is a protected hydrazine derivative featuring a tert-butoxycarbonyl (Boc) group and a 3-hydroxybenzyl moiety, serving as a versatile and crucial building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of pharmaceuticals and bioactive compounds where controlled reactivity and stability are paramount. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in medicinal chemistry and custom synthesis projects.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those containing hydrazide or hydrazone functional groups.
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and constrained scaffolds for drug discovery programs.
• Ligand and Chelator Preparation: Serves as a precursor for creating specialized ligands in catalysis or metal-chelating agents.
• Heterocyclic Chemistry: Employed in the synthesis of various nitrogen-containing heterocycles like pyrazoles and triazoles.
• Cross-linking Agent: Potential use in polymer chemistry and material science for creating specialized cross-linked networks.
• Bioconjugation Chemistry: Useful for modifying biomolecules due to the reactive hydrazine group protected by the acid-labile Boc group.

Basic Information

Product Name	n-Boc-N''-(3-Hydroxybenzyl)Hydrazine
CAS No.	162739-82-4
Molecular Formula	C₁₂H₁₈N₂O₃
Molecular Weight	238.28 g/mol
Synonyms	1-Boc-2-(3-hydroxybenzyl)hydrazine; tert-Butyl (2-(3-hydroxybenzyl)hydrazine-1-carbonyl); N-(tert-Butoxycarbonyl)-N'-(3-hydroxybenzyl)hydrazine; Boc-NH-NH-CH2-(3-HO-Ph); (3-Hydroxybenzyl)hydrazine, N-Boc-protected; 1-(tert-Butoxycarbonyl)-2-[(3-hydroxyphenyl)methyl]hydrazine; tert-Butyl [(3-hydroxybenzyl)hydrazinyl]formate
EINECS	Contact for details

Quality Control

Our n-Boc-N''-(3-Hydroxybenzyl)Hydrazine undergoes rigorous quality testing to ensure compliance with industry standards for research and development use. Certificates of Analysis (COA) are available upon request, detailing parameters such as purity, identity, and impurity profiles. We adhere to strict in-house quality protocols to ensure batch-to-batch consistency and reliability for your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.