Description

3-(3-Aminopropyl)-1,1,2-Trimethyl-Benz[E]Indolium Bromide Hydrobromide is a specialized cationic dye intermediate and a quaternary ammonium salt derivative of a benz[e]indole. This compound is valued for its role as a key precursor in the synthesis of functional dyes, particularly cyanine dyes, which are essential for high-sensitivity detection applications. It is primarily required by manufacturers in the biotechnology, diagnostic, and advanced materials sectors for developing fluorescent probes, nucleic acid stains, and photosensitizers.

Application

• Cyanine Dye Synthesis: A critical building block for producing near-infrared (NIR) and infrared (IR) cyanine dyes used in bioimaging and medical diagnostics.
• Fluorescent Probe & Label Manufacturing: Used to create sensitive fluorescent labels for detecting proteins, nucleic acids (DNA/RNA), and other biomolecules.
• Diagnostic Reagent Production: Serves as an intermediate in the formulation of reagents for PCR, gel staining, and flow cytometry.
• Photosensitizer Development: Employed in research and production of photosensitizers for photodynamic therapy (PDT) and other light-activated treatments.
• Optical Material Research: Utilized in the development of novel organic semiconductors, non-linear optical (NLO) materials, and dye-sensitized solar cells (DSSCs).
• Analytical Chemistry: Acts as a derivatization agent or a chromophore in various spectroscopic and chromatographic analytical methods.

Basic Information

Product Name	3-(3-Aminopropyl)-1,1,2-Trimethyl-Benz[E]Indolium Bromide Hydrobromide
CAS No.	162411-26-9
Molecular Formula	C19H24Br2N2
Molecular Weight	456.22 g/mol
Synonyms	1,1,2-Trimethyl-3-(3-aminopropyl)-1H-benz[e]indolium bromide hydrobromide; 3-(3-Aminopropyl)-1,1,2-trimethyl-1H-benz[e]indolium bromide, hydrobromide; Benz[e]indolium, 3-(3-aminopropyl)-1,1,2-trimethyl-, bromide, hydrobromide; 1H-Benz[e]indolium, 3-(3-aminopropyl)-1,1,2-trimethyl-, bromide, hydrobromide (1:1:1); Cy3 Amine Hydrobromide precursor; Trimethyl benzindolium aminopropyl bromide hydrobromide
EINECS	Contact for details

Quality Control

Our production of 3-(3-Aminopropyl)-1,1,2-Trimethyl-Benz[E]Indolium Bromide Hydrobromide adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and residual solvents is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange-red crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.