Description

7-Benzyloxy-4-Chloro-6-Methoxyquinazoline is a high-purity, advanced pharmaceutical intermediate characterized by its distinct quinazoline core structure. This compound is of significant commercial importance as a key building block in the synthesis of targeted therapeutic agents, particularly kinase inhibitors. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel oncology and anti-inflammatory treatments.

Application

• Pharmaceutical Intermediate: Critical precursor in the multi-step synthesis of small molecule kinase inhibitors for targeted cancer therapies.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new drug candidates.
• Chemical Synthesis: Serves as a versatile scaffold for further functionalization to create libraries of novel quinazoline derivatives.
• Biochemical Research: Employed as a reference standard or tool compound in biochemical assays to study enzyme inhibition mechanisms.

Basic Information

Item	Details
Product Name	7-Benzyloxy-4-Chloro-6-Methoxyquinazoline
CAS No.	162364-72-9
Molecular Formula	C16H13ClN2O2
Molecular Weight	300.74 g/mol
Synonyms	4-Chloro-7-(phenylmethoxy)-6-methoxyquinazoline; 6-Methoxy-7-benzyloxy-4-chloroquinazoline; 4-Chloro-6-methoxy-7-benzyloxyquinazoline; 7-Benzyloxy-4-chloro-6-methoxy-quinazoline; BOC Sciences Brand Name: BBL-PH-00166; 162364-72-9 (CAS Registry Number); 4-Chloro-7-benzyloxy-6-methoxyquinazoline
EINECS	Contact for details

Quality Control

Our 7-Benzyloxy-4-Chloro-6-Methoxyquinazoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical R&D and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.