Description

4-Chloro-6,7-diethoxyquinazoline is a high-purity, versatile quinazoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key synthetic intermediate in the development of targeted pharmaceutical agents and specialty fine chemicals. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in creating novel compounds for therapeutic and material science applications.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of tyrosine kinase inhibitors and other biologically active quinazoline-based drug candidates.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry programs, enabling the exploration of new chemical entities.
• Agrochemical Synthesis: Used in the development of novel herbicides and plant growth regulators that leverage the quinazoline core structure.
• Material Science: Acts as a building block for creating advanced organic materials, including ligands for metal-organic frameworks (MOFs) and specialty polymers.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	4-Chloro-6,7-diethoxyquinazoline
CAS No.	162363-46-4
Molecular Formula	C₁₂H₁₃ClN₂O₂
Molecular Weight	252.70 g/mol
Synonyms	6,7-Diethoxy-4-chloroquinazoline; 4-Chloro-6,7-diethoxy-quinazoline; Quinazoline, 4-chloro-6,7-diethoxy-; 162363-46-4; 4-Chloro-6,7-bis(ethoxy)quinazoline; 4-Chloro-6,7-diethoxy-quinazoline (CAS 162363-46-4); 4-Chloro-6,7-diethoxyquinazoline (major); 6,7-Diethoxy-4-chloro-quinazoline
EINECS	Contact for details

Quality Control

Our 4-Chloro-6,7-diethoxyquinazoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.