Description

4-(Trifluoromethyl)Thiophenylhydrazine Hydrochloride is a high-purity organofluorine building block essential for advanced chemical synthesis. This compound is valued for its trifluoromethylthiophene moiety, which imparts unique electronic and steric properties to target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the CF3 group enhances bioavailability and metabolic stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and proteomics research due to its reactive hydrazine group.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production of client-specific molecules.

Basic Information

Product Name	4-(Trifluoromethyl)Thiophenylhydrazine Hydrochloride
CAS No.	162258-86-8
Molecular Formula	C7H6ClF3N2S
Molecular Weight	242.64 g/mol
Synonyms	4-(Trifluoromethyl)thiophene-2-carbohydrazide hydrochloride; 2-Hydrazinyl-4-(trifluoromethyl)thiophene hydrochloride; 4-(Trifluoromethyl)-2-thienylhydrazine hydrochloride; (4-Trifluoromethylthiophen-2-yl)hydrazine hydrochloride; 2-Hydrazino-4-(trifluoromethyl)thiophene HCl
EINECS	Contact for details

Quality Control

Every batch of 4-(Trifluoromethyl)Thiophenylhydrazine Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and mass spectrometry, is supplied with each shipment to guarantee identity, purity, and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere after opening to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.