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Ethyl 2-Acetoxy-2-(Diethoxyphosphoryl)Acetate CAS NO 162246-77-7


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CAS No.:162246-77-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Ethyl 2-Acetoxy-2-(Diethoxyphosphoryl)Acetate is a high-purity organophosphorus compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique bifunctional structure, containing both phosphoryl and ester groups, makes it an essential reagent for constructing complex molecular architectures. This chemical is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those with phosphate ester or phosphonate functionalities.
  • Agrochemical Synthesis: Building block for creating advanced herbicides, insecticides, and plant growth regulators with enhanced activity.
  • Ligand and Catalyst Development: Used in the preparation of specialized phosphine-based ligands for asymmetric catalysis and metal complexation.
  • Peptide Mimetics and Prodrugs: Facilitates the incorporation of phosphonate groups into bioactive molecules to improve stability and bioavailability.
  • Material Science Research: Employed in the development of flame retardants, polymer modifiers, and specialty additives.
  • Chemical Biology Probes: Serves as a starting material for synthesizing activity-based probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name Ethyl 2-Acetoxy-2-(Diethoxyphosphoryl)Acetate
CAS No. 162246-77-7
Molecular Formula C10H19O7P
Molecular Weight 282.23 g/mol
Synonyms Diethyl (Acetoxy)(Ethoxycarbonyl)Methylphosphonate; (Acetoxy)(Ethoxycarbonyl)Methylphosphonic Acid Diethyl Ester; Ethyl (Diethoxyphosphoryl)(Acetoxy)Acetate; Acetic Acid [(Ethoxycarbonyl)(Diethoxyphosphoryl)Methyl] Ester; 2-(Diethoxyphosphoryl)-2-acetoxyacetic Acid Ethyl Ester; Diethyl [(Ethoxycarbonyl)(Acetoxy)Methyl]Phosphonate; (Acetoxy)(Ethoxycarbonyl)Methylphosphonate Diethyl Ester
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Quality Control

Our Ethyl 2-Acetoxy-2-(Diethoxyphosphoryl)Acetate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC analysis, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to minimize exposure to atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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