Description

1-Azabicyclo[3.2.1]Octan-6-One,(1R,5S)-(9Ci) is a high-purity, stereochemically defined bicyclic lactam that serves as a critical advanced pharmaceutical intermediate. This compound is valued for its rigid, three-dimensional scaffold, which is instrumental in the design and synthesis of novel bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to impart conformational rigidity to target molecules.
• Asymmetric Synthesis: Employed as a precursor or template in stereoselective chemical transformations.
• Neurological Drug Development: Potential scaffold for compounds targeting neurological receptors and enzymes.
• Chemical Biology Probes: Useful for creating molecular probes to study biological pathways and protein function.
• Academic & Industrial R&D: Serves as a valuable reagent in exploratory synthetic chemistry for novel heterocyclic systems.

Basic Information

Product Name	1-Azabicyclo[3.2.1]Octan-6-One,(1R,5S)-(9Ci)
CAS No.	162184-60-3
Molecular Formula	C7H11NO
Molecular Weight	125.17 g/mol
Synonyms	(1R,5S)-1-Azabicyclo[3.2.1]octan-6-one; (1R,5S)-6-Oxo-1-azabicyclo[3.2.1]octane; (1R,5S)-Tropinone; endo-Tropinone; (1R,5S)-8-Methyl-8-azabicyclo[3.2.1]octan-3-one (related skeleton); Bicyclic lactam intermediate; Tropane alkaloid derivative
EINECS	Contact for details

Quality Control

Our 1-Azabicyclo[3.2.1]Octan-6-One,(1R,5S)-(9Ci) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.