Description

6-Methoxy-7-Hydroxyquinazolin-4-One is a high-purity, advanced pharmaceutical intermediate with significant synthetic utility. This compound serves as a crucial building block in the development of novel, small-molecule therapeutics, particularly kinase inhibitors. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of tyrosine kinase inhibitors (TKIs) and other targeted cancer therapies.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up API (Active Pharmaceutical Ingredient) manufacturing processes.
• Biochemical Research: Employed as a reference standard or probe in enzymatic assays to study kinase activity and inhibition.
• Custom Synthesis: A versatile scaffold for the custom synthesis of novel quinazolinone derivatives for proprietary research programs.

Basic Information

Product Name	6-Methoxy-7-Hydroxyquinazolin-4-One
CAS No.	162012-72-8
Molecular Formula	C9H8N2O3
Molecular Weight	192.17 g/mol
Synonyms	7-Hydroxy-6-methoxyquinazolin-4(3H)-one; 4(3H)-Quinazolinone, 7-hydroxy-6-methoxy-; 6-Methoxy-7-hydroxy-4(3H)-quinazolinone; 6-Methoxy-7-hydroxy-3,4-dihydroquinazolin-4-one; 162012-72-8; Quinazolinone derivative intermediate
EINECS	Contact for details

Quality Control

Our 6-Methoxy-7-Hydroxyquinazolin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.