Description

4-Quinazolinamine, N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitro- is a high-purity, advanced pharmaceutical intermediate belonging to the quinazolinamine class of heterocyclic compounds. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential kinase inhibitors and other targeted small-molecule drugs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• Biochemical Tool Compound: Serves as a reference standard or probe in biochemical assays to study specific biological pathways.
• Fine Chemical Synthesis: Intermediate for the preparation of more complex, functionalized quinazoline derivatives with specialized properties.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	4-Quinazolinamine, N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitro-
CAS No.	162012-67-1
Molecular Formula	C15H8ClF2N4O2
Molecular Weight	348.70 g/mol
Synonyms	N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine; 7-Fluoro-6-nitro-N-(3-chloro-4-fluorophenyl)quinazolin-4-amine; 4-Amino-7-fluoro-6-nitro-N-(3-chloro-4-fluorophenyl)quinazoline; 162012-67-1; UNII-9J2Q8V8N8P; 9J2Q8V8N8P; Quinazolinamine derivative (3-chloro-4-fluoro, 7-fluoro-6-nitro)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.