Description

8-(Trifluoromethyl)Quinolin-5-Amine is a high-purity, fluorinated quinoline derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the quinoline scaffold and the electron-withdrawing trifluoromethyl group, which is essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the quinoline core.
• Material Science: Serves as a precursor for functional dyes, ligands, and organic electronic materials due to its aromatic and fluorinated structure.
• Chemical Biology: Employed as a probe or tag in biochemical research to study protein interactions and enzyme mechanisms.
• Catalyst Ligand Synthesis: Utilized to create specialized ligands for transition metal catalysts used in cross-coupling and other fine chemical reactions.

Basic Information

Product Name	8-(Trifluoromethyl)Quinolin-5-Amine
CAS No.	161431-57-8
Molecular Formula	C10H7F3N2
Molecular Weight	212.17 g/mol
Synonyms	5-Amino-8-(trifluoromethyl)quinoline; 8-Trifluoromethyl-5-quinolinamine; 5-Quinolinamine, 8-(trifluoromethyl)-; Quinolin-5-amine, 8-(trifluoromethyl)-; 8-(Trifluoromethyl)-5-quinolinamine; 8-Trifluoromethylquinolin-5-ylamine
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)Quinolin-5-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.