Description

8-Bromo-4-Hydroxy-5-Methoxy- Quinoline-3-Carboxylic Acid CAS NO 161405-29-4 is a high-purity, functionalized quinoline derivative serving as a critical building block in advanced organic synthesis. Its unique bromo-hydroxy-methoxy substitution pattern makes it a versatile intermediate for constructing complex molecular architectures with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting infectious diseases or cancer.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive quinoline core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts.
• Material Science Research: Employed in the synthesis of organic semiconductors, fluorescent dyes, and other functional organic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological processes and enzyme mechanisms.
• Academic and R&D: Fundamental building block for methodological development and exploration of new chemical reactions in university and industrial labs.

Basic Information

Product Name	8-Bromo-4-Hydroxy-5-Methoxy- Quinoline-3-Carboxylic Acid
CAS No.	161405-29-4
Molecular Formula	C₁₁H₈BrNO₄
Molecular Weight	298.09 g/mol
Synonyms	8-Bromo-4-hydroxy-5-methoxyquinoline-3-carboxylic acid; 5-Methoxy-8-bromo-4-hydroxyquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 8-bromo-4-hydroxy-5-methoxy-; 161405-29-4; 8-Bromo-5-methoxy-4-hydroxyquinoline-3-carboxylic acid; 4-Hydroxy-5-methoxy-8-bromoquinoline-3-carboxylic acid; 8-Br-4-OH-5-OMe-quinoline-3-COOH
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Hydroxy-5-Methoxy- Quinoline-3-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.