Description

8-Bromo-5-Methoxyquinolin-4-Ol is a versatile brominated quinoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated methoxyquinoline structure makes it a valuable building block for constructing complex molecules with tailored biological and photophysical properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting neurological disorders, infectious diseases, and oncology.
• Agrochemical Research: Used in developing novel fungicides, herbicides, and insecticides due to the bioactive quinoline core.
• Material Science & OLED Development: Serves as a building block for creating organic light-emitting diode (OLED) materials and other electronic chemicals.
• Coordination Chemistry & Ligand Synthesis: Utilized to prepare chelating ligands for metal complexes in catalysis and sensing applications.
• Dye & Pigment Intermediate: Acts as a precursor for the synthesis of specialized quinoline-based dyes and colorants.
• Academic & Contract Research: Essential reagent for methodological studies and library synthesis in medicinal and synthetic chemistry.

Basic Information

Product Name	8-Bromo-5-Methoxyquinolin-4-Ol
CAS No.	161405-28-3
Molecular Formula	C10H8BrNO2
Molecular Weight	254.08 g/mol
Synonyms	8-Bromo-5-methoxy-4-quinolinol; 4-Quinolinol, 8-bromo-5-methoxy-; 5-Methoxy-8-bromoquinolin-4-ol; 8-Bromo-5-methoxy-4-hydroxyquinoline; 161405-28-3; 8-Br-5-MeO-quinolin-4-ol
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Methoxyquinolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP compliance for pharmaceutical applications and can tailor specifications to meet your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.